kirazmattson
1863 posts
Jun 10, 2025
9:44 PM
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Tadalista 20 mg helps with erectile dysfunction (ED) by improving blood flow to the penis, making it easier to get and maintain an erection when sexually stimulated. Tadalista 20 mg Works (Mechanism of Action): Tadalista contains 20 mg of tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. Here's what it does in the body: Sexual arousal triggers the release of nitric oxide in the penis. Nitric oxide activates the enzyme guanylate cyclase, which increases levels of cGMP (cyclic guanosine monophosphate). cGMP relaxes the smooth muscles in the blood vessels of the penis, allowing more blood to flow in. This increased blood flow leads to an erection. Tadalafil blocks the PDE5 enzyme, which normally breaks down cGMP. By inhibiting PDE5, tadalafil prolongs cGMP activity, keeping the blood vessels dilated longer and helping maintain the erection. Tadalista 20 Mg Onset: 30 to 60 minutes after taking it Duration: Up to 36 hours (hence the nickname “weekend pill”) Dosage frequency: Usually once per day or as needed (not more than once daily) Requires sexual stimulation to work; it does not cause an erection on its own Do not use with nitrates (for chest pain) — can cause dangerous drops in blood pressure Avoid alcohol and grapefruit juice, which can increase side effects Side effects may include: headache, flushing, back pain, muscle aches, nasal congestion, or indigestion
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