Yes, Lost Mary vapes typically contain nicotine. Most Lost Mary disposable devices come pre-filled with e-liquid that includes nicotine, often in the form of nicotine salts. These nicotine salt formulas provide a smoother throat hit and faster absorption compared to traditional freebase nicotine. The nicotine strength can vary depending on the model and regional regulations, but common concentrations include 5% (50mg/mL). Always check the packaging or product details to confirm the nicotine content before purchasing.