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Double Marker Test: Purpose, Procedure, and Normal
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Redcliffe Labs
3 posts
Feb 13, 2025
9:11 PM
The Double Marker Test is a prenatal screening test that helps assess the risk of chromosomal abnormalities in a developing fetus, such as Down syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18). This blood test measures two key biomarkers—free beta hCG and PAPP-A—to evaluate the likelihood of genetic disorders. It is typically performed between the 9th and 14th weeks of pregnancy, often in combination with an ultrasound for more accurate results. The Double Marker Test is safe and non-invasive, helping doctors determine if further diagnostic tests are required for better prenatal care and informed decision-making.


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